Thursday, April 29, 2010

Arginine Increases Exercise Capacity

Taking arginine supplements can improve the cycling ability for people over 50. Researchers writing in the Journal of the International Society of Sports Nutrition tested a combination of the amino acid and an antioxidant in sixteen cyclists, finding that it enhanced their anaerobic threshold -- the amount of work done before lactic acid begins to accumulate in the blood.

The loss of exercise capacity with age often results in a reduction in physical fitness and more rapid senescence. A dietary supplement that increases exercise capacity might help to preserve physical fitness by optimizing performance and improving general health and well being in older people.

One way in which older people may reduce their exercise capacity revolves around the signaling molecule nitric oxide (NO), which is involved in many physiological processes, including those related to working out. NO production diminishes in quantity and availability as we age and is associated with an increased prevalence of other cardiovascular risk factors. In the body, NO is created from the amino acid arginine and is inactivated by oxygen free radicals. By supplementing diet with both the precursor and an anti-oxidant, the researchers hoped to support the NO system in the cyclists and thereby enhance performance.

Sixteen cyclists aged between 50 and 73 were randomly assigned to receive either the supplement or dummy placebo pills. After one week of study, the anaerobic threshold of the supplement group increased, while that of the control group did not significantly alter.

This study indicates a potential role of arginine and antioxidant supplementation in improving exercise performance in elderly.

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